GenePro: Frequently Asked Questions

WellPro is the Wellness Division of MDS. In this division we aim to improve your health, lifestyle and longevity by making use of the latest scientific advancements offering a focused approach to your health. We work with individuals with a great passion and interest in the area of nutrition and genetics giving you access to their professional services to answer your queries and offer assistance on your road to health and wellness. We look forward to helping you.

What does the word 'GenePro' mean?

GenePro is a combination of the words “genetic” and “profile”. This test provides personalised nutrition and lifestyle guidance that is key to health and wellness and is unique to your genetic make-up. The most exciting part about the GenePro test is that the mutations identified through testing can be “switched off or on”depending on your lifestyle and dietary choices. The test offers some guidance for making conscious lifestyle choices with the aim to reduce the risk of developing health conditions identified by the test and/or by known family medical history.

What is Nutrigenomics?

Nutrigenomics is the exciting new and exploding science where information from your personal genetic profile is combined with your nutritional profile and lifestyle factors to individualize and personalize a lifestyle and nutrition plan to reduce risk factors contributing to chronic diseases such as cardiovascular disease, cancer, inflammation, Type II diabetes, obesity etc. This is not a new diagnostic or prognostic tool for disease management but is a very powerful knowledge base for disease risk reduction through nutritional and lifestyle changes based on the identification of individual inherited gene mutations.

Why do I need to know if I have a mutation?

Some specific mutations – in very specific areas of a gene – can alter the normal effect of the protein or enzyme to cause significant physiological and biochemical changes. These changes may lead to an increased risk for chronic disease development when expressed in the presence of specific negative environmental conditions as well as certain nutritional deficiencies.

What is the difference between High penetrance and Low penetrance mutations?

Certain mutations will cause genetic abnormalities or disease in spite of optimal environmental and/or nutritional conditions and these are called high-penetrance mutations. Thus environmental influences play little or no part in the expression of these genes. Huntington disease is as a good example of such a mutation. This triplet repeat expansion has little or no influence from environmental factors and is considered fully penetrant. Low-penetrance mutations on the other hand are influenced to a greater extent by external (environmental) influences. Nutrition, lifestyle and environmental factors play a major role in the expression of these mutations in contributing to chronic disease e.g. cardiovascular disease, cancer, obesity, Type 11 diabetes and chronic inflammatory conditions. These mutations are what we look at in the GenePro test.

Where can I have the test done?

In South Africa, any Dis-Chem pharmacy or the Wellness Warehouse on Kloof Street in Cape Town is also familiar with our test; they will charge to take the sample. Various healthcare providers can also take your DNA sample for you, or we can send you a kit for you to collect your DNA yourself which you can then post back to us. This requires just a finger prick blood sample. For more information and to obtain a list of healthcare providers – refer to our “contact us” section.

Do I need to give a whole blood sample for the test?

No. We only need a small finger prick sample of blood.

Who will interpret the results for me?

Post-test nutrigenomic counselling is imperative in adding value to the DNA GenePro test and must be performed by a qualified professional. This is one of the primary reasons your results will only be sent to your health practitioner and not directly to you. The correct interpretation and understanding of the test results is vital to the long-term outcome of the investment in your own health and wellness. Our qualified staff shall also be able to assist you and refer you on to a relevant health practitioner.

Who should have a Genetic test?

Any person with any of the following conditions:

– Early onset cardiovascular disease
– Thrombosis, including deep vein thrombosis
– Sporadic cancer
– Obesity
– Type II diabetes
– Chronic inflammatory conditions – arthritis, asthma, eczema etc.
– Iron overload
– Family history of any of the above health conditions, or dementia/Alzheimer disease

Any person who would like a risk reduction strategy for:

– Chronic disease risk reduction in general
– Cardiovascular disease risk reduction
– Sporadic (general) cancer risk reduction
– Weight problems

Do you have any further questions?

We will be happy to assist you with further information regarding our tests and services. Please contact us.